She initially planned to become a model, but was told that she was not tall enough at 5’5″ to be a runway model and should instead focus on commercials. After taking commercial and acting classes, she fell in love with acting and realized that she preferred it over modeling. Greene graduated from high school early and moved to L.A. to pursue an acting career. Since then, she has appeared as a guest on many popular television programs, such as Punk’d and Crossing Jordan.
Greene’s big break came in 2008 when she was cast as Alice Cullen in Twilight, a film based on the novel of the same name by Stephenie Meyer. She reprised her role as Alice in the 2009 sequel to Twilight, The Twilight Saga: New Moon, 2010’s The Twilight Saga: Eclipse, and will reprise the role again in 2011, in The Twilight Saga: Breaking Dawn Part 1 and Part 2.
Greene portrayed Michelle Burkham in the drama film Skateland, which premiered at the 2010 Sundance Film Festival.
She reunited with her Twilight co-star Kellan Lutz in the movie Warrior and also stars in thriller film, Summer’s Blood, as well as the Dark Castle Entertainment production The Apparition, which began filming on February 1, 2010.
Appearing nude in a bodypainted bikini, Greene posed for SoBe advertisements that ran in the 2010 issue of the Sports Illustrated Swimsuit Edition. People Magazine named Greene as one of the “World’s Most Beautiful Women of 2010”. She received “The Style Icon Award” at Hollywood Life’s Young Hollywood Awards this year. Greene was also presented an award from the PETA foundation for representing Avon and their no testing on animals policy.